What is bombay blood group?
Answers:
The Bombay phenotype arrises from a recessive gene that results in the inability to build the A or B bodies on cell that give bloodtype, cause what could possibly be an AB bloodtype genetically to test as O blood type.
(m)
Experts inform that a dying out genotype (blood group) of people be detected in Mumbai, a few decades rear, who neither had A, AB, B or O group. This unusual genotype was characterized as the Bombay Blood Group. If a Bombay Blood Group recipient is not transfused the blood of a Bombay Blood Group party, it can lead to a haemolytic transfusion response, which can be fatal and organize to death.
AB+
A unusual genotype (blood group) of people be detected in Mumbai, a few decades spinal column, who neither had A, AB, B or O group of blood. This bloody genotype was characterized as the Bombay Blood Group. If a Bombay Blood Group recipient is not transfused the blood of like group he can die of a haemolytic transfusion reaction occurring as a result of direct red cell lysis because of the presence of anti H antibodies in the serum of Bombay Blood Group patients. Studies reveal that this is due to the malingering of the H substance (antigen) in the red cell. The absence of the H substance is attributed to the not as much as of the enzyme fucosyl transferase. The Bombay Blood Group phenotypes lack H antigen surrounded by the red cells and own anti-H in the serum.
Family studies hold shown that the Bombay phenotype, called as Oh, is due to the presence contained by homozygous state of a rare recessive gene. The precursor protein from which the blood group proteins are formed is term as the H substance. This is bio-chemically produced.
More about it:
Experts voice that if proper blood grouping or testing practices is not followed, it can organize to people beside Bombay blood group not being detected. According to Dr Mukesh Desai, during cell grouping or routine grouping, Bombay Blood Group would be categorised as O group because they wouldn’t show any repercussion to anti-A and anti-B antibodies just approaching a normal O group. When a cross parallel with different blood loads of O group is done, then it would show cross-reactivity or incompatibility. Therefore reverse grouping or Serum grouping have to be performed to detect the Bombay Blood group.
Other issues related to Bombay Blood Group are that blood is incompatible near all A, B and O donors. In routine forward grouping, this blood group would grant reaction as an ’O’ blood group where on earth as in serum grouping it would show spontaneous effect with ’O’ cell due to the presence of anti H in their serum. Once detected, are registered at Institute of Immuno-haematology (IIH)) for further studies as very well as for availability of information regarding the donors of this group.
Since Bombay Blood Group is the rarest of the sporadic group; it is desirable to develop cryopreservation facilities for scarce donor units. Every blood guard can easily argue a rare blood type donor database from amongst their regular voluntary donors. If the blood banks can borrow or exchange dying out blood units surrounded by times of need, lot of problems related to singular blood groups like Bombay Blood Group can be solved. This is just possible if each blood hill has a voluminous number of committed regular voluntary donors.
The wrong notion among people call for to be dispelled that of the possibility of getting infections like HIV1 through blood donation. The public requirement to be informed that there is no approach a donor can get such infection through blood donation.
It is a pink blood type called the Bombay blood group. People next to the Bombay blood group have the A and/or B genes but tryout as an O.
For the A and B genes to do their job, they obligation another gene, H. If someone has two broken H genes, later their blood cells look close to an O person’s blood cells even if they enjoy the A and/or B genes.
Let’s say someone have an A gene and two broken H genes. Why do they look like an O? First sour, we need to remember that that blood testing looks at our blood cells not our genes. If someone looked at this guy’s genes, they’d verbs he had A type blood.
What a blood experiment looks at are proteins that are stuck on the outside of the red blood cells. (Remember, genes are in recent times instructions for making certain proteins. So the H gene make the H protein, the A gene, the A protein, etc.) Blood type A means the A protein is near, B means the B protein is in that and O means neither is near.
What this guy’s A gene does is make a protein that turns the H protein into the A protein. If he doesn't brand name any H protein, then he can’t sort any A protein—there is no A protein on his red blood cells. So, he looks O but is genetically A.
What happen when someone with the Bombay blood group have kids? Most likely their masked A and B genes will be seen surrounded by their children. So for our example above, the results might look like this:
A B
O AO BO
O(A) AA AB
Now as you can see, AB is possible.
Another channel for an apparent O to own an AB child is if the “O” parent has one of a couple of pink subtypes of the A gene. These genes with name like Ax (Ao) or Am breed very little A protein. So little, surrounded by fact, that the protein check sometimes misses it and the person can be mistaken for an O.
There are extra tests that can be done to distinguish these A subtypes from O but they aren’t other done (probably because the subtypes are so rare).
"O" positive
It is a blood group in which the A or B gene for ABO blood grouping cannot be expressed.
OH blood group is bombay blood group..
empire bearing this blood group will not possess A,B AND H antigens within their red cells.
They own anti A, anti B and anti H antibodies ..
their sera are incompatible with adjectives red cells except those near same rare blood groups
it be called so beacuse Bhende et al reported that first contained by BOMBAY.
More Questions & Answers...
- why use galactose-fed animals as diabetes models?
- Why does the rice have got more gens than human?
- Is it safe to have social intercourse with my Chinese friends?
- Is Diffuse Histiocytic Lymphoma, also known as Hodgkin's Lymphoma, a curable disease?
- What is conditioned media?
- If cats have nine lives then why don't scientists perform experiments on them instead of rabbits?
- Has anyone of you ever glued a piece of broken tooth back onwith superglue, if so what happened?
- Has Anyone In The Medical Proffession Come across A Real Life Vampire?