Statistics of embryonic stem cell research?

I have be doing some reading of the various review articles on esc research and have discovered that seriously of times their statistical analysis is flawed (I'm a mathematician, not a clinical researcher). For example, if an experiment studied 20 rats and 8 of them died, most of the time the result of those 8 rats are not included in the final analysis, showing a much greater rate of "cure" than there actualy be. Has anyone else noticed this? Has anyone done a literature review to see if this is prevailant within the science literature? Could I just own had too small of a taste of the literature?

Answers:
In medical research it is common to remove subjects from a study. In clinical trials the mortality of the subject could be the result from a factor except the treatment. For instance if radiation is used on the subjects to knock out their bone marrow to be replaced with esc donor matter, and the subject dies of radiation related reasons, the subject could be discounted. The donor substance was not the issue surrounded by the death of the subject. In human trials the most adjectives answer is non-compliance with some aspect of treatment.

In adjectives the literature there should be a footnote, or even a paragraph, as to why the subjects be removed. Some journals do not print the full study and the condensed version may shortage the finer details needed to be mathematically correct.

Should you decide to meet a literature review I would suggest getting raw facts from the researchers and interviewing them on their statistical methods. It will become clearer as to why particular subjects be removed.

G'day Sophia,

Thank you for your question.

I haven't looked much of the publication articles as opposed to reports surrounded by the popular press.

If you think that in that is a trend there, you should look at it as a project. If the statistical analysis be flawed in some of the findings, that should enjoy some impact on consideration of this controversial topic.

Regards

ByeDr.com

Statistics of embryonic stem cell research?

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