Pharmacological issues?
Answers:
Synergism is when two or more agents act together to realize an outcome greater than any one of them acting alone could. A common example of this is the use of meperidine (Demerol) and promethazine (Phenergen) together for strain control. Demerol will provide, say, x amount of dull pain relief. Phenergen will provide possibly 1/2 x amount of pain nouns. However, if used together, Demerol and Phenergen can provide 2-4 x amount of pain nouns.
Antagonism is when two agents act against one another. An example of this is opiates (such as Morphine and Heroin) and naloxone (Narcan). Morphine binds to specific receptor sites on cell (opiod receptors). Narcan also binds to these receptor sites, but with a stronger bond and in actuality displaces Morphine from these sites.
Sorry, I do not recall coming across the possession indifference as specifically used in pharmacology. Could this be reffering to tolerence, and/or to the breakdown of the cells/body to respond to an agent?
compatability, conflict, disinterest
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